Google maps for tissues: Multiscale imaging of biological systems and disease

Multiscale models for biological systems

a r t i c l e i n f o Life, amazingly rich in diversity of shapes and functions, explores the limits of extreme complexity in nature. In this review we shall discuss in general terms the use of multiscale mathematical and computer models to study the dynamics of biological systems. These models permit integration of the rapidly expanding knowledge concerning the molecular basis of biology and i...

Multiscale analysis of biological systems.

It is argued that multiscale approaches are necessary for an explanatory modeling of biological systems. A first step, besides common to the multiscale modeling of physical and living systems, is a bottom-up integration based on the notions of effective parameters and minimal models. Top-down effects can be accounted for in terms of effective constraints and inputs. Biological systems are essen...

Microwave Imaging of Biological Tissues

Optical characterization and imaging of biological tissues

The biological tissues exhibit their distinct optical characteristics. Their point-to-point compositional variation could either be determined by the optical parameters or reconstruction of the reflectance or tomographic images. The optical parameters, absorption and reduced scattering coefficients of goat tissues and human post-mastectomy breast specimen are determined by matching of their ref...

Microwave-induced acoustic imaging of biological tissues

We present tomographic imaging of biological tissues by use of microwave-induced acoustic signal. It was demonstrated that the acoustic signal was proportional to the intensity of the incident microwave and was related to the absorption property of microwave in the medium. Pulsed microwave radiation was used to illuminate the samples. Absorbed microwave energy caused thermoelastic expansion tha...